Simulating the ESP32 in Proteus is a powerful way to test IoT designs before building physical hardware, though it requires manual setup as Proteus does not include ESP32 support by default. By adding third-party libraries, you can simulate core functions like GPIO, UART, I2C, and SPI communication.
Proteus requires a compiled binary ( .hex or .bin ) to execute the simulation. Arduino IDE hex file export issue proteus esp32 simulation