The brothers return to Chicago to destroy The Company from within. Sara Tancredi is framed for murder. Kellerman switches sides. These episodes are more political thriller than escape drama.
To summarize the answer to :
FBI Agent Alexander Mahone (William Fichtner) is introduced to hunt the escapees. The Treasure: prison break how many episodes in season 2 updated
The drive self-destructed seven seconds later. Prison Break: How Many Episodes in Season 2