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Autodesk’s EULA explicitly forbids:
AutoCAD 2010 relies heavily on Microsoft’s .NET Framework 3.5 and specific Visual C++ runtimes (2005, 2008). These are system-level components that must be installed via Windows Installer. You cannot "copy-paste" these dependencies onto a USB drive. Portable.Autodesk.AutoCAD.2010
AutoCAD 2010 is a legacy version of Autodesk's design software, and using a "Portable" version typically refers to a modified, non-standard installation that runs without a full system setup Portable
: Running software from a portable device can also introduce security considerations, especially if the device is used across multiple, untrusted computers. You cannot "copy-paste" these dependencies onto a USB drive
It is worth noting that Official portable applications are typically labeled as "Portable" or "App" by the vendor (e.g., "AutoCAD Portable").